Aruna Kamineni, PhD, MPH, came to Kaiser Permanente Washington Health Research Institute in 2009 with a wealth of experience in chronic disease epidemiology. Dr. Kamineni has expertise in using case-control methods to evaluate screening efficacy, and her research focuses on addressing evidence gaps for clinical guidelines, particularly for cervical and colorectal cancer prevention. A substantial portion of her work has focused on developing infrastructure and methods for research using electronic clinical and administrative health care data.
Since 2011, Dr. Kamineni has participated in the National Cancer Institute’s Population-based Research to Optimize the Screening Process (PROSPR) consortium to evaluate and improve cancer screening in U.S. community settings. As a principal investigator for multisite cervical and colorectal cancer PROSPR Research Centers, Dr. Kamineni is leading and collaborating on work to determine how to optimally use screening tests and consider how to tailor screening for population subgroups.
Dr. Kamineni’s research goals include studying the impact of human papillomavirus (HPV) DNA testing and HPV vaccination on cervical cancer and screening programs. Multidisciplinary collaboration is a valued and important driver of Dr. Kamineni’s research and she embraces a team science approach to optimizing cancer prevention.
Cervical cancer; colorectal cancer; screening; disparities
Electronic clinical and administrative data infrastructure development for research; case-control studies; team science
Selby K, Sedki M, Levine E, Kamineni A, Green BB, Vachani A, Haas JS, Ritzwoller DP, Croswell JM, Ohikere K, Doria-Rose VP, Rendle KA, Chubak J, Lafata JE, Inadomi J, Corley DA. Test performance metrics for breast, cervical, colon and lung cancer screening: a systematic review. J Natl Cancer Inst. 2023 Feb 8:djad028. doi: 10.1093/jnci/djad028. [Epub ahead of print]. PubMed
Del Vecchio NJ, Beaber EF, Garcia MP, Wheeler CM, Kamineni A, Chao C, Chubak J, Corley DA, Owens CL, Winer RL, Pruitt SL, Raine-Bennett T, Feldman S, Silverberg M. Provider- and facility-level variation in pre-cancerous cervical biopsy diagnoses. J Low Genit Tract Dis. 2023 Jan 17. doi: 10.1097/LGT.0000000000000721. [Epub ahead of print]. PubMed
Kruse GR, Lykken JM, Kim EJ, Haas JS, Higashi RT, Atlas SJ, McCarthy AM, Tiro JA, Silver MI, Skinner CS, Kamineni A. Provider beliefs in effectiveness and recommendations for primary HPV testing in three healthcare systems. JNCI Cancer Spectr. 2023 Feb; 7(1): pkac086. Published online 2022 Dec 5. doi: 10.1093/jncics/pkac086. PubMed
Feldman S, Lykken JM, Haas JS, Werner CL, Kobrin SC, Tiro JA, Chubak J, Kamineni A. Factors associated with timely colposcopy following an abnormal cervical cancer test result. Prev Med. 2022 Oct 18;164:107307. doi: 10.1016/j.ypmed.2022.107307. [Epub ahead of print]. PubMed
Kamineni A, Doria-Rose VP, Chubak J, Inadomi JM, Corley DA, Haas JS, Kobrin SC, Winer RL, Lafata JE, Beaber EF, Yudkin JS, Zheng Y, Skinner CS, Schottinger JE, Ritzwoller DP, Croswell JM, Burnett-Hartman AN. Evaluation of harms reporting in U.S. cancer screening guidelines. Ann Intern Med. 2022 Sep 27. doi: 10.7326/M22-1139. Online ahead of print. PubMed
Chubak J, Dalmat RR, Weiss NS, Doria-Rose VP, Corley DA, Kamineni A. Informative presence in electronic health record data: a challenge in implementing study exclusion criteria. Epidemiology. 2023 Jan 1;34(1):29-32. doi: 10.1097/EDE.0000000000001542. Epub 2022 Sep 20. PubMed
Chao CR, Chubak J, Beaber EF, Kamineni A, Mao C, Silverberg MJ, Tiro JA, Skinner C, Garcia M, Corley DA, Winer RL, Raine-Bennett T, Feldman S, Wheeler CM. Gaps in the screening process for women diagnosed with cervical cancer in four diverse US health care settings. Cancer Med. 2022 Sep 15. doi: 10.1002/cam4.5226. Online ahead of print. PubMed
Dalmat RR, Ziebell RA, Kamineni A, Phipps AI, Weiss NS, Breslau ES, Corley DA, Green BB, Halm EA, Levin TR, Schottinger JE, Chubak J. Risk of colorectal cancer and colorectal cancer mortality beginning ten years after a negative colonoscopy, among screen-eligible adults 76-85 years old. Cancer Epidemiol Biomarkers Prev. 2022 Sep 13:EPI-22-0581. doi: 10.1158/1055-9965.EPI-22-0581. [Epub ahead of print]. PubMed
Chubak J, Burnett-Hartman AN, Barlow WE, Corley DA, Croswell JM, Neslund-Dudas C, Vachani A, Silver MI, Tiro JA, Kamineni A. Estimating cancer screening sensitivity and specificity using healthcare utilization data: defining the accuracy assessment interval. Cancer Epidemiol Biomarkers Prev. 2022 Aug 2;31(8):1517-1520. doi: 10.1158/1055-9965.EPI-22-0232. PubMed
Beaber EF, Kamineni A, Burnett-Hartman AN, Hixon B, Kobrin SC, Li CI, Oliver M, Rendle KA, Skinner CS, Todd K, Zheng Y, Ziebell RA, Breslau ES, Chubak J, Corley DA, Greenlee RT, Haas JS, Halm EA, Honda S, Neslund-Dudas C, Ritzwoller DP, Schottinger JE, Tiro JA, Vachani A, Doria-Rose VP. Evaluating and improving cancer screening process quality in a multilevel context: the PROSPR II consortium design and research agenda. Cancer Epidemiol Biomarkers Prev. 2022 Aug 2;31(8):1521-1531. doi: 10.1158/1055-9965.EPI-22-0100. PubMed
How KPWHRI is contributing to better cancer screening and better outcomes for patients.
Aruna Kamineni, PhD, MPH, discusses her recent study on how guidelines report screening risks.
Research informs care as Kaiser Permanente Washington, exceeding 80 percent screening rate, launches home-based 'FIT First' pilot.
Managed Healthcare Executive, Dec. 8, 2022